Tsc1 antibody

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August undefined, 2024

WebAnti TSC1 pAb [Catalog No.: ATL-HPA074132] Toggle menu. Compare ; Phone: 760-431-4600 / Fax: 760-431-4604; Sign in or Register; Cart 0. Search. CURRENT PROMOTIONS. ... Primary Antibodies; Aicardi-Goutieres syndrome . All Aicardi-Goutieres syndrome; Labeled Proteins; Recombinant Antibodies; Alcohol Use Disorder . All Alcohol Use Disorder; WebTuberous sclerosis complex (TSC) is an autosomal dominant disorder that is due to inactivating mutations in TSC1 (also known as hamartin) or TSC2 (also known as tuberin). TSC is featured by benign tumors (hamartomas ... (TSC1) (clone 1B2-2A8) antibody (upper). Proteins were visualized using a goat anti-mouse-IgG secondary antibody conjugated to ...

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WebAnti-TSC1 Antibody has been tested for use in ELISA, Western Blotting, Immunocytochemistry and Immunofluorescence. Specific conditions for reactivity should be optimized by the end user. Expect a band at approximately 130 kDa in Western Blots of specific cell lysates and tissues. WebAnti-TSC1 antibodies are offered by a number of suppliers. This target gene encodes the protein 'TSC complex subunit 1' in humans and may also be known as Hamartin, LAM, truncated hemartin, and tuberous sclerosis 1 protein. Structurally, the protein is reported to be 129.8 kilodaltons in mass. Based on gene name, fly, ... cynthia huffman seattle

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WebAntibody was affinity purified using an epitope specific to TSC1 immobilized on solid support. The epitope recognized by A300-316A maps to a region between residue 1100 and the C-terminus (residue 1164) of human tuberous sclerosis 1 using the numbering given in Swiss-Prot entry Q92574 (GeneID 7248). Web"Phospho-Hamartin/TSC1 (Ser511) antibodies" comparison. At Proteintech, we pride ourselves on our antibody quality, customer service and transparency. As such, we are … WebRabbit anti Human TSC1 antibody recognizes an epitope within the internal region of the 130kDa tumour suppressor protein, Tumour sclerosis complex 1 (TSC1). Mutation within … billy\u0027s stone crab fl

hamartin Antibody (C-8) SCBT - Santa Cruz Biotechnology

WebIgGy Antibody Selector – Quickly search hundreds of thousands of antibodies available for purchase from VWR by selecting common antibody features like antigen symbol and name, reactivity, clonality, conjugation, host, and other key factors. Antibodies used to identify and locate intracellular and extracellular proteins in common applications such as Western … WebFeb 4, 2024 · Tuberous sclerosis complex subunit 1 (TSC1) and 2 (TSC2) are frequently mutated in non–small cell lung cancer (NSCLC), however, their effects on antitumor immunity remained unexplored.A CRISPR screening in murine Kras G12D /Trp53 −/− (KP) model identified Tsc1 and Tsc2 as potent regulators of programmed cell death ligand 1 … cynthia hughes obituaryWebProduct Description. Mouse anti Human TSC1 antibody recognizes TSC1, also known as hamartin and tuberous sclerosis 1 protein. TSC1 encodes a growth inhibitory protein thought to play a role in the stabilization of tuberin. Mutations in TSC1 have been associated with tuberous sclerosis. Alternative splicing results in multiple transcript ... billy\u0027s stone crab florida

"WebFeb 25, 2024 · hamartin Antibody (C-8) is an IgG 2b κ mouse monoclonal hamartin antibody (also designated TSC1 antibody or TSC antibody) suitable for the detection of the hamartin protein of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA. hamartin Antibody (C-8) is available as both the non-conjugated anti-hamartin antibody form, as well as … " - Tsc1 antibody

Tsc1 antibody

WebThis is supported by experiments showing overexpression of TSC1 and TSC2 results in a significant decrease in the GTP/GDP ratio bound to Rheb and the inhibition of cell growth. A shorter 40 kDa isoform of TSC1 has been shown to exist but its function is unknown. Application Note. Anti-TSC1 Antibody has been tested for use in ELISA and Western ... WebThis phospho-TSC1 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS312 of mouse TSC1. Storage. Aliquot the phospho-TSC1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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WebFeb 5, 2024 · How activated B cells build biosynthetic pathways and organelle structures necessary for subsequent robust antibody secretion is still unclear. The dominant model holds that nascent plasma cells adapt to increased antibody synthesis by activating the unfolded protein response (UPR) under the control of the transcription factor Xbp1. Web5.2 TSC1–TSC2 complex. TSC1 and TSC2 genes were identified in 1997 and 1993 as the genetic loci mutated in the disease known as tuberous sclerosis complex (TSC) (European TSC Consortium, 1993; van Slegtenhorst et al., 1997). These genes’ products are two proteins, TSC1 and TSC2, which do not share any homology between them, and very little ...

WebAntibodies. We have a collection of 534,170 monoclonal and polyclonal antibodies to most target proteins. They cover all major research species, applications, and are available in multiple conjugated forms. Our IHC-plus™ antibodies are highly characterized for use in FFPE human tissue Immunohistochemistry. WebImmunohistochemical analysis of paraffin-embedded mouse skeletal muscle tissue slide using 29906-1-AP (Hamartin/TSC1 antibody) at dilution of 1:500 (under 10x lens). Heat …

WebRabbit recombinant monoclonal mTOR (phospho S2448) antibody [EPR426(2)] - BSA and Azide free. Validated in WB, IHC, Dot and tested in Mouse, Human. WebEach TSC1 Antibody is fully covered by our Guarantee+, to give you complete peace of mind and the support when you need it. Our TSC1 Antibodies can be used in a variety of model …

WebImmunoprecipitation of TSC1 was performed on HAP1 cell lysates. Antibody-bead conjugates were prepared by adding 2 µg of TSC1 polyclonal antibody (Product # PA5 …

WebTSC1 or TSC2 genes were deleted by the CRISPR/Cas9 system. (E) Western blot to phospho-S6K. Control and TSC1 or TSC2 knockout preadipocytes were starved or starved and restimulated with amino acids, as indicated (dashed … billy\u0027s stone crab fort lauderdaleWebMonoclonal Antibody for studying Hamartin/TSC1. Cited in 10 publications. Validated for Western Blotting. Highly specific and rigorously validated in-house, Hamartin/TSC1 (1B2) Mouse Monoclonal Antibody (CST #4963) is … cynthia hughes january 6WebThis antibody binds to Yeast LCB2. Format: Liquid or Lyophilized: Storage: Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use: Purity > 90% was determined by SDS-PAGE: Purification: Purified with Protein A or G affinity chromatography: Cellular Localization: Endoplasmic reticulum; Other locations billy\u0027s stone crab in tierra verde floridaWebHerein, we show that a recombinant fusion protein of a humanized antibody to CD40 fused to HPV16.E6/7 (αCD40-HPV16.E6/7) can evoke HPV16.E6/7-specific CD8+ and CD4+ T-cell responses in head-and ... cynthia hughes mdWebAntibodies that detect TSC1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, Dot blot and ELISA. These antibodies … billy\u0027s stone crab dinner menuWebNov 12, 2024 · TSC1/2-mutated PEComas sometimes respond to mTOR-inhibition therapy , but these drugs are mechanistically believed to be inefficient in TFE3-altered PEComa. MET-inhibitors, on the other hand, are active in alveolar soft part sarcoma with TFE3 rearrangement [ 20 ], a rare subtype of soft-tissue sarcoma, and could constitute a … cynthia hughes nephewWebDr. Constantinos Demetriades is a Molecular Cell Biologist and a European Research Council (ERC) Grantee. Currently, he holds a Max Planck Research Group Leader position (Associate Professor level) at the Max Planck Institute for Biology of Ageing (MPI-AGE) in Cologne. His work focuses on the intricate molecular and cellular mechanisms of nutrient sensing and … cynthia hughes in tn