WebONO-RS-082 Phospholipase inhibitor Replaces Prod. #: ALX-270-115 Phospholipase A2inhibitor (IC50=7 µM for purified guinea pig lung PLA2). Inhibits epinephrine-stimulated thromboxane production in human platelets (86% at 3.5µM). Also blocks insulin secretion in pancreatic islets in response to glucose. WebONO-RS-082 has been shown to be a potent PLA2 (phospholipase A2) and epinephrine inhibitor. More specifically this compound has been reported to inhibit epinephrine-stimulated thromboxane production in human platelets. Studies also suggest that this agent inhibits substance P induced histamine release from peritoneal mast cells.
ONO-RS-082 CAS#:99754-06-0 Chemsrc
WebONO-RS-082 是一种磷脂酶 A (phospholipase A; PLA) 抑制剂。 ONO-RS-082 抑制 PLA2 , IC 50 为 1.0 μM,但即使浓度达到 100 μM 也不抑制 PLC。 MCE 的所有产品仅用作科学 … Web20 de nov. de 2009 · Using the reversible PLA 2 antagonist, ONO-RS-082 (ONO) and live-cell, time-lapse microscopy to image the Golgi reassembly process, we found that Golgi mini-stacks underwent a burst of membrane tubule formation following washout of ONO: before washout only 4.3 ± 3.8 tubules/cell/10 min were formed, whereas after washout … cif 飛行機
Effect of phospholipase A2 inhibitors on mouse T lymphocytes. I ...
WebThe phospholipase A2 (PLA2) inhibitors, quinacrine, p-bromophenacyl bromide, ONO-RS-082, aristolochic acid and chloracysine blocked the priming effect of LHRH, but not acute LHRH-induced gonadotrophin release measured … WebHere, we investigate the antibiotic properties of a compound, ONO-RS-082 (ONO), which was identified by bacterial cytological profiling as operating via a novel MoA. We found … Web1 de ago. de 1997 · We examined whether metabolites of arachidonic acid (AA) regulate K+ efflux during regulatory volume decrease (RVD) by mudpuppy red blood cells (RBCs). … cif 陸送