Myh6 mercremer

Author: olek

August undefined, 2024

WebIn this study, we generated a Myh6-Cre knockin mouse model by inserting the IRES-Cre-wpre-polyA cassette between the translational stop codon and the 3' untranslated region of the endogenous Myh6 gene. By crossing knockin mice with the Rosa26 reporter lines, we found that Myh6-Cre targeted cardiomyocytes at the embryonic and postnatal stages. WebMyh6-Mcm: Myosin heavy chain 6-MerCreMer; F/M: female/male; HR: heart rate; bpm: beats per minute; AWT: anterior wall thickness; LVPWT: left ventricular posterior wall thickness; LVEDD: left ventricular end diastolic diameter; LVEDDi: LVEDD indexed to body weight; LVESD: left ventricular end systolic diameter; LVFS: left ventricular fractional …

Genetic ablation of Cullin-RING E3 ubiquitin ligase 7 …

Web22 mrt. 2024 · Heart disease is the leading cause of death worldwide. The major cause of heart failure is the death of the myocardium caused by myocardial infarction, detrimental … Web9 sep. 2024 · Myh6 encodes one of two myosin heavy chain proteins for cardiac contraction 32, and the Myh6 promoter has been used to express Cre or CreER in cardiomyocytes. Tg (Myh6-cre)2182Mds drives... unknown reboot target edl

Myh6 Cre Esr1 1jmk J Mercremer Mice The Jackson Laboratory

WebGenetic inactivation of β-catenin in the Myh6-Mcm Tam Dsp F/F mice prolonged survival, improved cardiac function, reduced cardiac arrhythmias, and attenuated myocardial … Web18 dec. 2024 · During the past two decades, experiments utilizing constitutive as well as tamoxifen-activated Myh6-driven Cre recombinase transgenes have driven remarkable … Web23 jul. 2015 · Mhy6 encodes a cardiac muscle specific protein: alpha-myosin heavy chain. Here, we generated a new Myh6-MerCreMer (Myh6MerCreMer/+) inducible Cre knock … recent wolf sightings in illinois

Full article: Autophagic degradation of CCN2 (cellular …

A1cf Mouse shRNA Plasmid (Locus ID 69865) from OriGene …

WebFor example, experiments utilizing a tamoxifen-activated transgene termed Myh6-merCremer (Sohal et al., 2001), the product of which (merCremer) responds to tamoxifen by translocating from the cytoplasm to the nucleus, have been cited in more than 250 instances according to the PubMed database. WebMutations in theLMNAgene encoding nuclear lamins A/C cause a diverse array of tissue-selective diseases, with the heart being the most commonly affected organ. Despite … recent wolf sightings in yellowstoneWeb1 jul. 2024 · Genetic fate mapping was performed using an inducible, cardiomyocyte specific Myh6-MerCreMer mouse model, crossed with a LacZ reporter. A single large dose of tamoxifen successfully labelled 70–80% of cardiomyocytes when administered at P0, and was followed by apical resection at P2. unknown realtek hardware

"WebThe MerCreMer-FRT-Neo-FRT cassette was inserted into the Myh6 locus (6 bp upstream ATG). The Neo cassette was removed by crossing Myh6MerCreMer-Neo/+ mice with … " - Myh6 mercremer

Myh6 mercremer

Generation and characterization of a Myh6-driven Cre knockin …

Web15 dec. 2012 · Neither the heterozygous Myh6-MerCreMer/LepR flox/WT nor the Myh6-MerCreMer mice exhibited any overt signs of heart failure as observed in the … Web23 jul. 2015 · Here, we generated a new Myh6-MerCreMer (Myh6(MerCreMer/+)) inducible Cre knock-in mouse by inserting a MerCreMer cassette into the Myh6 start codon. By …

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Web22 dec. 2024 · Myh6-MerCreMer Tg/0 mice were crossbred with Cul7 flox/flox mice to obtain Cul7 flox/flox Myh6-MerCreMer Tg/0 and Cul7 +/+ Myh6-MerCreMer Tg/0 control … Web15 sep. 2024 · The most widely used gene for driving heart-specific Cre expression is α-myosin heavy chain (Myh6) . Inducible Cre recombinase using Myh6 promoter has also …

Web23 jul. 2024 · To investigate the role of PDGFR-β in heart regeneration, we conditionally activated PDGFR-β signaling in CMs by intercrossing the Myh6-MerCreMer strain with … WebTg (Myh6-cre/Esr1*)1Liao Transgene Detail Summary Transgene origin Transgene description Recombinase activity Phenotypes Disease models Find Mice (IMSR) …

Web23 jul. 2015 · Myh6 MerCreMer/+ Hearts Display Normal Structure and Function before and after Tamoxifen Induction. Given that Myh6 MerCreMer/+ is a knock-in/knock-out allele … WebProduct Specs; Item A1cf Mouse shRNA Plasmid (Locus ID 69865); Company OriGene Technologies; Price Pricing Info Supplier Page View Company Product Page; Catalog …

Web8 jun. 2024 · We generated Myh6-MerCreMer;Confetti +/− (MCM;Confetti) mice in which a single dose of tamoxifen leads to stochastic, indelible labeling of cardiomyocytes with 1 of 4 fluorescent proteins (Figure [A]). 4 By pulsing tamoxifen at postnatal day (P) 0 to P1, before significant binucleation or polyploidization occurs, 1,2 we ensured that labeled …

Web31 jul. 2014 · Notably, Myh6 (α-MHC)-MerCreMer transgenic mice, 1 where Cre activity is induced by the application of tamoxifen or raloxifene, have become a valuable tool for … recent wolf sightings in ohioWeb22 jul. 2015 · (A) Schematic diagram of gene targeting. The MerCreMer-FRT-Neo-FRT cassette was inserted into the Myh6 locus (6 bp upstream ATG). The Neo cassette was … recent worcester ma obituariesWeb19 jan. 2024 · Myh6-MerCreMer +; Tead1 W/W mice treated with PBS (Control + PBS) or Nec (Control + Nec) served as additional controls. b Echocardiographic measurement of … recent women\u0027s mma fightsWeb27 nov. 2024 · In this system, Myh6-MerCreMer:R26R-Confetti-labelled cells and their daughter cells could express one of four different fluorescent reporters: nGFP, YFP, RFP or mCFP. Fig. 4 Gel–miR-302-induced... unknown reboot target fastbootWeb13 sep. 2024 · Here, we generated a new Myh6-MerCreMer (Myh6(MerCreMer/+)) inducible Cre knock-in mouse by inserting a MerCreMer cassette into the Myh6 start codon. unknown rebelWeb18 dec. 2024 · Myh6-driven Cre recombinase activates the DNA damage response and the cell cycle in the myocardium in the absence of loxP sites. Regeneration of muscle in the … unknown reboot target emergencyWebThe Jackson Laboratory myh6 mercremer b6 fvb 129 a1cftg myh6 cre esr1 1jmk j Myh6 Mercremer B6 Fvb 129 A1cftg Myh6 Cre Esr1 1jmk J, supplied by The Jackson Laboratory, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more recent woody harrelson movie