WebJan 11, 2024 · Hydrochlorothiazide (HCTZ) and chlorthalidone are both thiazide diuretics recommended as first-choice options for treating high blood pressure because of their benefits on heart health and overall death rates. So, which one is better? Let’s look at the evidence. Chlorthalidone is better at lowering blood pressure. WebThiazide diuretics remain the drugs of first choice for treating hypertension in the African-American hypertensive. The calcium channel blockers (CCBs) are attractive alternatives to thiazides in patients uncontrolled by or intolerant of thiazides or who have specific indications for these agents (eg, angina, severe diastolic dysfunction).

First-line medicines in the treatment of hypertension

WebJoint National Committee 8 recommends initial therapies of a thiazide diuretic or CCB in black patients, but does not provide specific guidance on the best second agent to choose. In general, it recommends adding a CCB, thiazide diuretic, ACE-I, or ARB as a second drug if a patient is not responding to monotherapy. WebFinally, the current debate on whether thiazide diuretics are the first-choice drug for most patients with uncomplicated hypertension, as stated in the Seventh Joint National … swisslife caen

Hypertension Treatment With Diuretics Recommended In New Guide

WebThe choice of thiazide-like diuretic usually depends on the person's comorbidities, local recommendations, and cost. Where possible, prescribe a drug that is taken only once a … Web• Thiazide diuretic • Calcium channel blocker (CCB) At blood pressure goal? Strategy Description A Start one drug, titrate to maximum dose, and then add a second drug. B … WebPrescrire Int. 2014 Sep;23(152):215-20. PMID: 25325125. Abstract. We concluded in 2004 that the first-choice treatment for hypertension in adults was single-agent therapy with … swisslife cbpec